Leveraging Applications of Formal Methods, Verification, and Validation Theoretical Computer Science and General Issues : Springer : 9783642165573 : 3642165575 : 19 Oct 2010 : This volume contains the conference proceedings of the 4th International S- posium on Leveraging Applications of Formal Methods, Veri?cation and Vali- tion, ISoLA 2010, which was held in Greece (Heraklion, Crete) October 18?21, 2010, and sponsored by EASST. Following the tradition of its forerunners in 2004, 2006, and 2008 in Cyprus and Chalchidiki, and the ISoLA Workshops in Greenbelt (USA) in 2005, in Poitiers (France) in 2007, and in Potsdam (Germany) in 2009, ISoLA 2010 p- vided a forum for developers, users, and researchers to discuss issues related to the adoption and use of rigorous tools and methods for the speci?cation, ana- sis, veri?cation, certi?cation, construction, testing, and maintenance of systems from the point of view of their di?erent application domains. Thus, the ISoLA series of events serve