How can research into culturally responsive and sustaining education (CRSE) inform and transform science teaching and learning? What approaches might teachers use to study CRSE in their classrooms? What are teachers learning from their research that might be transferable to other classrooms and schools?In this practical resource, teacher researchers from the Culturally Responsive and Sustaining Education Professional Learning Group based in New York City provide insights for educators on how to address complex educational and sociocultural issues in the science classroom.Highlighting wide-ranging and complex problems such as the COVID-19 pandemic and racial injustice and how they affect individual science instruction settings, with a particular focus on urban and high-need school environments, chapters examine and describe what CRSE is and means for science teaching.Through individual and collaborative research studies, chapters help readers understand various approaches to developing