Soft-sensing and Decoupling Control in Microbial Fermentation Process : LAP Lambert Academic Publishing : 9786200095183 : 6200095183 : 21 May 2019 : The soft-sensing and optimal control of microbial fermentation process has become an important research content in the biotechnology field. It is of great significance to improve the level of equipment automation, promote the innovation of biotechnology technology, improve production efficiency and economic efficiency.In this book, the inverse soft sensing model of fermentation process is constructed by combining inverse system method and least square support vector machine theory(LS-SVM), LS-SVM is used to approximate the nonlinear function which is difficult to express explicitly in the inverse soft-sensing model, and the support is established. Secondly, in order to realize decoupling and optimal control of multivariable nonlinear systems, the inverse control method of LS-SVM is proposed, and the inverse system method is combined with I