Formulation and Evaluation of a Floating Drug Delivery System : Independent Aurthor : 9781805450726 : 1805450727 : 13 Nov 2022 : The high level of patient compliance in taking oral dosage forms is due to the ease of administration and handling of these forms [1]. Development of a successful oral controlled release formulation requires an understanding of three aspects: (a) gastrointestinal physiology (b) physiochemical properties of the drug and (c) dosage form characteristics [2]. In the development of oral controlled drug delivery system, one of the main challenges is to modify the GI transit time [1]. Using controlled release technology, oral delivery for 24 h(hours) is possible for many drugs; however, the substance must be well absorbed throughout the whole gastrointestinal tract. A significant obstacle may arise if there is a narrow window for drug absorption in the gastro intestinal tract (GIT), if a stability problem exists in gastrointestinal fluids, or the drug is poorly solu