Seachem Safe is the complete and super-concentrated dry conditioner for both fresh and salt water. Safe removes chlorine, chloramine and detoxifies ammonia, nitrite, and nitrate. Seachem Safe is non-acidic and will not impact pH. A further bonus for the reef hobbyist: Seachem Safe will not over-activate skimmers. Seachem Safe may be used during tank cycling to alleviate ammonia/nitrite toxicity. It contains a binder which renders ammonia, nitrite, and nitrate non-toxic, allowing the biofilter to more efficiently remove them. Use Seachem Safe at start-up and whenever adding or replacing water. When transporting or quarantining fish, use Seachem StressGuard. When adding new fish, use Seachem Stability. Both are ideal for use with Seachem Safe. Application of Seachem SafeUse 200 mg of Seachem Safe (included scoop) per each 200 L of aqaurium water as needed to reduce chlorine and chloramine or per 50 L of aquarium water for ammonia. May be added to aquarium directly, but better if added to