Translational Neuroimmunology in Multiple Sclerosis : Academic Press : 9780128019146 : 012801914X : 10 Aug 2016 : Multiple Sclerosis (MS) is the most common disabling neurological disease of young adults, although it can also affect children and adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the amount of damage and the nerves that are affected. People with severe cases of MS may lose the ability to walk or speak clearly. Although there is not currently a cure for MS, therapies can help treat MS attacks, manage symptoms and reduce progress of the disease. This book will provide an overview of recent findings and knowledge of the Neuroimmunology of Multiple Sclerosis and the translation of this research to immunotherapy treatment. Chapters will include the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers, pharmacogenetics and responses to therapy. Immunomodulatory therapies current