Structural Studies on HIV Reverse Transcriptase Related to Drug Discovery David K. Stammers and Jingshan Ren Zidovudine, Lamivudine, and Abacavir Monica Carten and Harold Kessler Stavudine, Didanosine, and Zalcitabine Gail Skowron, Sapna Chowdhry, and Michael R. Stevens Emtricitabine Gail Skowron, Jeffrey Bratberg, and Rudi Pauwels Nucleotide Analogs Craig J. Hoesley Resistance to Nucleoside and Nucleotide Reverse Transcriptase Inhibitors Nancy Shulman and Mark Winters Pharmacokinetics of Reverse Transcriptase Inhibitors Patrick Hoggard, Stephen Kewn, Saye Khoo and David Back Peripheral Neuropathy Associated With Nucleoside Reverse Transcriptase Inhibitor Therapy Bruce A. Cohen and Russell Bartt Mitochondrial Dysfunction and Nucleoside Reverse Transcriptase Inhibitor Therapy A Pathophysiological Perspective William Lewis Mitochondrial Toxicity and Lipodystrophy Grace McComsey Nevirapine David Asmuth and Richard Pollard Efavirenz Graeme J. Moyle and Brian Conway Delavirdine Brian Conway