p1. Chapter 1 - The Tumour Microenvironment and Circulating Tumour Cells A partnership driving metastasis and glycan-based opportunities for cancer controlpp2. Chapter 2 - Dormancy in the Tumor Microenvironmentpp3. Chapter 3 - Tumor-associated tertiary lymphoid structures A cancer biomarker and a target for next-generation immunotherapypp4. Chapter 4 - Studying the tumor microenvironment in zebrafishpp5. Chapter 5 - Pre-metastatic niche formation by neutrophils in different organspp6. Chapter 6 - Tumor cell invasion and the tumor microenvironment Special focus on brain tumorspp7. Chapter 7 - The dog as a model to study the tumor microenvironmentpp8. Chapter 8 - EFFEROCYTOSIS AND THE STORY OF FIND ME'', ''EAT ME AND DON'T EAT ME SIGNALING IN THE TUMOR MICRO ENVIRONMENTpp9. Chapter 9 - Color-coded imaging of the tumor micro-environment TME in human patient-derived orthotopic xenograft PDOX mouse modelsp10. Chapter 11 - Mitochondria and the tumor microenvironment in blood cancerppp11. Cha