Acknowledgement...Preface...Table of Contents...Contributing Authors...brPart I In Vitro Toxicological High Throughput Screening Methodsbr1. Cell-Based Assays to Identify ERR and ERRPGC ModulatorsCaitlin Lynch, Jinghua Zhao, and Menghang Xiabr2. Mitochondrial Membrane Potential AssaySrilatha Sakamuru, Jinghua Zhao, Matias S. Attene-Ramos, and Menghang Xiabr3. Cell-Based hERG Inhibition Assay in a High-Throughput FormatJinghua Zhao, and Menghang Xia br4. Identifying CAR Modulators Utilizing a Reporter Gene AssayCaitlin Lynch, Jinghua Zhao, Hongbing Wang, and Menghang Xiabr5. Study Liver Cytochrome P450 3A4 Inhibition and Hepatotoxicity Using DMSO-Differentiated HuH-7 CellsYitong Liubr6. Acetylcholinesterase Inhibition Assays for High-Throughput ScreeningShuaizhang Li, Andrew J. Li, Michael F. Santillo, and Menghang Xiabr7. Cell-Based Assays to Identify Modulators of Nrf2ARE PathwayZhengxi Wei, Jinghua Zhao, Li Zhang, and Menghang XiabrPart II In Vitro Toxicological High Content Screenin