pChapter 1. Stem Cell Therapy Significance and Applications of Stem Cell Products in the Tissue Engineering and Regenerative Medicine.- Chapter 2. GLP Requirements of Stem Cells.- Chapter 3. Current Good Manufacturing Practice CGMP Facility and Production of Stem Cell.- Chapter 4. Global Regulatory Frameworks and Quality Standards for Stem Cells Therapy and Regenerative Medicines.- Chapter 5. Stem Cell Bioreactors Design, Structure and Operation of Stem Cell Bioreactors.- Chapter 6. Stem Cell Culture and Expansion Role of culture, Types of Cells, Growth Conditions, Media Nutrients, Growth Factors, Growth Phase Cycle.- Chapter 7. UP Scaling of Clinical Grade Stem Cell Production-Upstream Processing USP and Downstream Processing DSP Operations of Cell Expansion, Harvesting, Detachment, Separation, Washing and Concentration Steps, and the Regulatory Requirements.- Chapter 8. Characterization of Clinical-Grade Stem Cells Microscopic, Cellular, Molecular, and Functional Characterization of