pWith its wide spectrum of data, case studies, monitoring, and experimental and numerical simulation techniques, the multidisciplinary approach of material, environmental, and computer science applied to the conservation of cultural heritage offers several opportunities for the heritage science and conservation community to map and monitor state-of-the-art knowledge on natural and human-induced climate change impacts on cultural heritage--mainly constituted by the built environment--in Europe and Latin America. Geosciences' Special Issue titled Preservation of Cultural Heritage and Resources Threatened by Climate Change was launched to take stock of the existing but still fragmentary knowledge on this challenge, and to enable the community to respond to the implementation of the Paris agreement. These 10 papers exploit a broad range of data derived from preventive conservation monitoring conducted indoors in museums, churches, historical buildings, or outdoors in archeological sites an