The book is divided into four parts: the first part introduces the basic concepts of nicotinamide coenzyme, the synthesis of nicotinamide coenzyme, intracellular distribution, and an overview of the main functions and detection methods so that readers can quickly understand the general feature and function of nicotinamide coenzyme; the second part describes the involvement of nicotinamide coenzyme in intracellular signal transduction and its role in cellular physiological and biochemical processes to explain exactly how nicotinamide coenzyme works in it and enable readers to deeply understand the principle of nicotinamide coenzyme playing an important function; the third part describes the role of nicotinamide coenzyme in the pathophysiological process of the disease, tries to illustrate the specific mechanisms of their association with the occurrence of the disease, and points out the potential value in future translational medicine research; the fourth part introduces the production