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ENbook.hu

In a world where hearts beat in pixelated sync and love is just a click away, Rachel Laferriere's book, Dopa, offers an unfiltered glimpse into the tumultuous universe of online dating. With uninhibited intensity, she delves into the lives of souls searching for connections in the vast void of cyberspace, where the line between authenticity and illusion blurs, and the human heart is both strengthened and shattered.brThrough her captivating verses, Laferriere explores the unbridled emotions that fuel the fires of outrage. From social injustices to the desolate cries of the forgotten, she gives voice to the silenced masses, urging readers to confront the uncomfortable truths lurking beneath the surface of their lives. Dopa, is a poignant testament to the power of anger as a catalyst for change, a clarion call for revolution, and an exorcism of the demons that dwell within society's darkest corners.brAt the heart of this poetic scream, lies the enigmatic power of perception. Laferriere ma

Dopa | Laferriere Rachel | Keménykötésű

Parkinson's disease affects the central nervous system, thus impacting vital motor skills. The most common symptoms are motor related. Rigidity, tremor, postural instability and slowness of movement are common signs of the disease. Other recognized symptoms are related to gait and posture disturbances such as festination, freezing of gait, mask-like facial expression, a slurred monotonous quiet voice, etc. Cognitive deficits can also occur. These include executive dysfunction, problems with abstract thinking, lack of cognitive flexibility, attention deficit, uninhibited action, etc. The primary pathological mechanism of Parkinson's disease is cell death in the brain's basal ganglia. The chief line of defense against the deterioration of motor functions due to Parkinson's disease is a set of drugs comprising of levodopa, MAO-B inhibitors and dopamine agonists. Surgery, subcutaneous waking day apomorphine infusion, deep brain stimulation and enteral dopa pumps may also be used after the 

Parkinson's Disease: Symptoms, Pathophysiology and Treatment | Walsh Aubrey | Keménykötésű

pAlthough  sup18supFfluorodeoxyglucose FDG generally shows an excellent performance as a cancer-imaging agent when using PET-CT, there are some settings in which other radiopharmaceuticals offer advantages. Such non-FDG tracers are now gaining widespread acceptance not only in research but also in clinical practice. This atlas, including about 500 high-quality images, is a user-friendly guide to PET-CT imaging beyond FDG. A wide range of tracers is covered, such as sup18supF- and sup11supC-choline, sup11supC-methionine, sup18supF-ethyl-L-tyrosine, sup68supGa-DOTA-NOC, sup11supC-acetate, sup11supC-thymidine, and sup18supF-DOPA. Throughout, the emphasis is on image interpretation, with guidance on the recognition of normal, benign, and malignant uptake and clear instruction on learning points and pitfalls. This atlas is designed to serve as a reference text for both nuclear physicians and radiologists, and will also be of great benefit to radiographers, technologists, and nuclear medicin

PET | CT Beyond FDG: A Quick Guide to Image Interpretation | Fanti Stefano | Keménykötésű

This book introduces molecular imaging and Target Therapy in various cancers. The first part is the subjects and primary focused on the basics of nuclear physics, radiation dosimetry, nuclear medicine equipment and small animal imaging equipment. The second part is about the radiopharmaceutical and commonly used clinical radiopharmaceuticals, including positron emission imaging agent, single photon emission imaging agent, and radionuclide therapy agents as well as their radioactive preparation, quality control, and a brief clinical application were included. Also, this part introduces a number of new imaging agents which were potential value of clinical applications. In the third part, the clinical application of the conventional imaging agent 18F-FDG in different tumors and neurodegenerative diseases and 18F-Dopa imaging in the nervous system are discussed. Besides the clinical applications of 99mTc labeled radiopharmaceuticals in parathyroid disease, coronary heart disease, myocardia

Nuclear Medicine in Oncology: Molecular Imaging and Target Therapy | Huang Gang | Keménykötésű

pThis volume of emPharmaceutical Biocatalysisem starts with a discussion on the importance of biocatalytic synthesis approaches for a sustainable and environmentally friendly production of pharmaceuticals and active pharmaceutical ingredients. Among the enzymes discussed in detail with respect to their pharmaceutical relevance are cyclic nucleotide phosphodiesterases playing an important role in modulating signal transduction in various cell types human DOPA decarboxylase, related to Parkinson's disease and aromatic amino acid decarboxylase deficiency and phospholipase D enzymes as drug targets. Isocitrate dehydrogenase 1 and 2 mutations are novel therapeutic targets in acute myeloid leukemia. An additional chapter is devoted to the use of enzymes for prodrug activation in cancer therapy. The other topics include small-molecule inhibitors targeting receptor tyrosine kinases in cancer, 946-Lactams and related compounds as antibacterials, non-vitamin K oral anticoagulants for the treatme

Pharmaceutical Biocatalysis: Important Enzymes, Novel Targets, and Therapies | Grunwald Peter | Keménykötésű

At the time when Parkinson's Disease is diagnosed in a patient, roughly two thirds of dopaminergic neurons of substantia nigra are already degenerated. The onset of the disease must, therefore, be much earlier. This book deals with early diagnosis and early preventive treatment which may sustain the process underlying the disease. By use of psychometric, kinesiologic, physiologic, histologic, biochemical, endocrinologic, pharmacologic and imaging techniques, including positron-emission tomography and brain mapping, specialists tried to focus on new diagnostic criteria. New methods including psychometric evaluation, apparative measurement of movement, analysis of peripheral blood and urinary constituents have supplemented this approach. It has been agreed that early preventive therapy consists of low dosis of L-DOPA plus benserazide, L-deprenyl and dopaminergic agonists.

Early Diagnosis and Preventive Therapy in Parkinson's Disease | Przuntek Horst | Keménykötésű

pbA Top 10 Science Book of Fall 2015 - iPublishers WeeklyibbrbbbrbA star science journalist with Parkinson's reveals the inner workings of this perplexing disease bbrbbbrSeven million people worldwide suffer from Parkinson's, and doctors, researchers, and patients continue to hunt for a cure. In iBrain Stormsi, the award-winning journalist Jon Palfreman tells their story, a story that became his own when he was diagnosed with the debilitating illness. br Palfreman chronicles how scientists have worked to crack the mystery of what was once called the shaking palsy, from the earliest clinical descriptions of tremors, gait freezing, and micrographia to the cutting edge of neuroscience, and charts the victories and setbacks of a massive international effort to best the disease. He takes us back to the late 1950s and the discovery of L-dopa. He delves into a number of other therapeutic approaches to this perplexing condition, from partial lobotomies and deep brain stimulation to neural graf

Brain Storms: The Race to Unlock the Mysteries of Parkinson's Disease | Palfreman Jon | Keménykötésű

EAN: 9781999956295"Leader Geoffrey""Denor Pr" 2019

Parkinson's Disease: How to Optimise ON | OFF Periods during L | dopa Therapy | Leader Geoffrey | Keménykötésű

iAwakeningsi--which inspired the major motion picture--is the remarkable story of a group of patients who contracted sleeping-sickness during the great epidemic just after World War I. Frozen for decades in a trance-like state, these men and women were given up as hopeless until 1969, when Dr. Oliver Sacks gave them the then-new drug L-DOPA, which had an astonishing, explosive, awakening effect. Dr. Sacks recounts the moving case histories of his patients, their lives, and the extraordinary transformations which went with their reintroduction to a changed world.

Awakenings | Sacks Oliver | Keménykötésű

pbA star science journalist with Parkinson's reveals the inner workings of this perplexing diseasebppSeven million people worldwide suffer from Parkinson's, and doctors, researchers, and patients continue to hunt for a cure. In iBrain Stormsi, the award-winning journalist Jon Palfreman tells their story, a story that became his own when he was diagnosed with the debilitating illness.pp Palfreman chronicles how scientists have worked to crack the mystery of what was once called the shaking palsy, from the earliest clinical descriptions of tremors, gait freezing, and micrographia to the cutting edge of neuroscience, and charts the victories and setbacks of a massive international effort to best the disease. He takes us back to the late 1950s and the discovery of L-dopa. He delves into a number of other therapeutic approaches to this perplexing condition, from partial lobotomies and deep brain stimulation to neural grafting. And he shares inspiring stories of brave individuals living with

Neural Systems of Reinforcement for Drug Addiction From Actions to Habits to Compulsion and from Ventral to Dorsal Striatum.- Impact of Basic Research on Clinical Practice Clinical and Preclinical Perspectives.- Cell Genesis and Migration in the Basal Ganglia in Health and Disease.- Oscillations in the Basal Ganglia Network Cellular Mechanisms and Pathological Aspects.- Stem Cells.- Up-Down States.- Deep Brain Stimulation.- Respecting Your Elders Why Subcortical Connections with the Basal Ganglia are Important.- Understanding Mechanisms of L-Dopa Induced Side-Effects.- Behavioral Correlates of Basal Ganglia Function and Dysfunction.- Computational Models of the BG From Molecules and Membranes to Behaviour and Cognition.- Genetic Aspects of Movement Disorders.- Basal Ganglia, Reward and Drug Seeking.- Index.

The Basal Ganglia IX | Groenewegen Hendrik Jan | Keménykötésű

pAbove all you have given us hope, help and a means to manage this disease. R. McNally, County Dublin, Ireland This timely volume provides an easily accessible and scientifically referenced source of information on the diverse aspects of drugs and nutrition. Professor Leslie Findley, Medical Advisor to The European Parkinson's Disease Association To me, nutrition now forms the platform for drug therapy and other contributory factors to my well-being. To anyone with or touched by Parkinson's, I commend this book to you. It is an indispensable tool to help you to help yourself... Read on and reap the benefits  Tom Isaacs, Co-Founder, The Cure Parkinson's Trust, UK In timing the L-dopa as the book says, I feel much better  V. R., PD Person, Southampton, UK The REVISED EDITION of this groundbreaking book offers a powerful blending of nutritional and pharmaceutical benefits, presenting the latest drugs and nutrients in the therapeutic approach and management of Parkinson's disease. In user-

Parkinsons Disease Reducing Symptoms with Nutrition and Drugs. 2017 Revised Edition | Leader G. | Keménykötésű

Parkinson 's DiseaseTop Tips to Optimize FunctionThe Top Tips offered in this user-friendly book, are distilled from the many years of successful clinical experience of the authors, directors of their pioneering Parkinson 's Management Team, in London, UK.It is greatly comforting for people with Parkinson 's to know that these really excellent tips can offer effective tools to optimize their function and wellbeing abilities, at any stageThis book is a MUST for people with Parkinson s, their Partners and Caregivers to confidently make informed choices within the constraints of the illness. The many positive tips include The Specific Timing of taking L-dopa and other Drugs with Food Avoiding Drug-Nutrient and Inter-Nutrient Interactions Movement Recommendations include Unfreezing, Getting up, Balance, Dance, Movement Therapy, Feet, Hands, Circulation and many others  Understanding How Dopamine is made from Dietary Protein and other Nutrients Dopamine, Adrenaline and the Stress Connection

Parkinson's Disease Top Tips to Optimize Function 2018 Revised Edition | Leader Lucille | Keménykötésű

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Curaprox Regular Refill CPS 14, 5 db, Tartalék fogköztisztító kefe  férfiaknak, A praktikus Curaprox Regular Refill CPS 14 fogköztisztító kefe pótfej a régi helyére tehető és így ismét garantált a szájüreg tökéletes ápolása.  Tulajdonságok:  a régi fogkefefej lecserélésére szolgál tökéletesen eltávolítja a szennyeződéseket a fogak közötti hézagokból csökkenti a fogszuvasodás kialakulásának veszélyét meggátolja a fogínygyulladás és a kellemetlen szájszag létrejöttét könnyen cserélhető  Használata: Cserélje le a régi kefefejet a pótfejre. Helyezze a fogkefét a fogközbe, majd előre és hátra mozgatva tisztítsa meg.

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