pForeword. Schizophrenia Spectrum Disorders Insights from views across 100 years.- 1. The schizophrenia construct after 100 years of challenges.- 2. Diagnosis and classification of the schizophrenia spectrum disorders.- 3. Toward Multidimensional Continuum Model of functional psychoses for research purposes.- 4. Irving Gottesman and the schizophrenia spectrum.- 5. Schizotypy Reflections on the bridge to schizophrenia and obstacles on the road ahead to etiology and pathogenesis.- 6. Autism spectrum disorders and schizophrenia.- 7. One hundred years of insanity genomic, psychological, and evolutionary models of autism in relation to schizophrenia.- 8. Quantifying the dynamics of central systemic degeneration in schizophrenia.- 9. Schizophrenia runs in some families, but where are the genes- 10. Changes in gene expression in subjects with schizophrenia associated with disease progression.- 11. Amino acids in schizophrenia -- glycine, serine and arginine.- 12. Developmental consequences of